CS1 (CD319) | CD molecules | IUPHAR Guide to IMMUNOPHARMACOLOGY

Top ▲

CS1 (CD319)

Target id: 2850

Nomenclature: CS1 (CD319)

Family: CD molecules

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     CS1 (CD319) has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 335 1q23.1-q24.1 SLAMF7 SLAM family member 7
Mouse 1 333 1 H2 Slamf7 SLAM family member 7
Rat 1 342 13q24 Slamf7 SLAM family member 7
Previous and Unofficial Names
CRACC | CS1-L | CD2-like receptor-activating cytotoxic cells
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia

Download all structure-activity data for this target as a CSV file

Antibodies
Key to terms and symbols Click column headers to sort
Antibody Sp. Action Affinity Units Reference
elotuzumab Hs Binding 8.1 pKd 2
pKd 8.1 (Kd 8.86x10-9 M) [2]

References

Show »

1. Kim JR, Mathew SO, Patel RK, Pertusi RM, Mathew PA. (2010) Altered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythematosus. Clin. Exp. Immunol., 160 (3): 348-58. [PMID:20345977]

2. Williams M, Tso JY, Landolfi NF, Powers DB, Liu G. (2010) Therapeutic use of anti-CS1 antibodies. Patent number: US7709610. Assignee: Facet Biotech Corporation. Priority date: 28/05/2003. Publication date: 04/05/2010.

How to cite this page

CD molecules: CS1 (CD319). Last modified on 15/05/2017. Accessed on 16/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2850.