neural cell adhesion molecule 1 (CD56) | CD molecules | IUPHAR Guide to IMMUNOPHARMACOLOGY

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neural cell adhesion molecule 1 (CD56)

Target id: 2769

Nomenclature: neural cell adhesion molecule 1 (CD56)

Abbreviated Name: NCAM1

Family: CD molecules

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     neural cell adhesion molecule 1 (CD56) has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 884 11q23.2 NCAM1 neural cell adhesion molecule 1
Mouse 1 1115 9 A5.3 Ncam1 neural cell adhesion molecule 1
Rat 1 858 8q23 Ncam1 neural cell adhesion molecule 1
Gene and Protein Information Comments
Several isoforms of human CD56 have been identified. The longest protein, isoform 5, is listed in the table above. The Entrez gene; 4684 and Uniprot: P13591 records have further details of all of the isoforms currently identified. We also list the longest isoform (3) of the mouse CD56 protein (Entrez Gene, Uniprot P13595).
Database Links
CATH/Gene3D
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
General Comments
CD56 is used as an immunohistochemical marker for neuroendocrine tumours.

References

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1. Dalbeth N, Gundle R, Davies RJ, Lee YC, McMichael AJ, Callan MF. (2004) CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation. J. Immunol., 173 (10): 6418-26. [PMID:15528382]

2. Poli A, Michel T, Thérésine M, Andrès E, Hentges F, Zimmer J. (2009) CD56bright natural killer (NK) cells: an important NK cell subset. Immunology, 126 (4): 458-65. [PMID:19278419]

How to cite this page

CD molecules: neural cell adhesion molecule 1 (CD56). Last modified on 06/02/2017. Accessed on 16/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2769.