Vesicular polyamine transporter | SLC18 family of vesicular amine transporters | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Vesicular polyamine transporter

Target id: 2556

Nomenclature: Vesicular polyamine transporter

Abbreviated Name: VPAT

Systematic Nomenclature: SLC18B1

Family: SLC18 family of vesicular amine transporters

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     Vesicular polyamine transporter has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 456 6q22.3-q23.3 SLC18B1 solute carrier family 18 member B1
Mouse - 459 10 A3-A4 Slc18b1 solute carrier family 18, subfamily B, member 1
Rat - - 1p12 Slc18b1 solute carrier family 18 member B1
Previous and Unofficial Names
Solute carrier family 18 member B1 | solute carrier family 18, subfamily B, member 1 | solute carrier family 18
Database Links
Specialist databases
Bioparadigms SLC Tables SLC18B1 (Hs)
Other databases
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
RefSeq Nucleotide
RefSeq Protein
UniProtKB
Wikipedia
Substrates and Reaction Kinetics
Substrate Sp. Property Value Units Standard property Standard value Assay description Assay conditions Comments Reference
spermine Hs - - 1
spermidine Hs - - 1

References

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1. Hiasa M, Miyaji T, Haruna Y, Takeuchi T, Harada Y, Moriyama S, Yamamoto A, Omote H, Moriyama Y. (2014) Identification of a mammalian vesicular polyamine transporter. Sci Rep, 4: 6836. [PMID:25355561]

2. Takeuchi T, Harada Y, Moriyama S, Furuta K, Tanaka S, Miyaji T, Omote H, Moriyama Y, Hiasa M. (2017) Vesicular Polyamine Transporter Mediates Vesicular Storage and Release of Polyamine from Mast Cells. J. Biol. Chem., 292 (9): 3909-3918. [PMID:28082679]

How to cite this page

SLC18 family of vesicular amine transporters: Vesicular polyamine transporter. Last modified on 09/03/2017. Accessed on 16/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2556.