decoy receptor 3 | Tumour necrosis factor (TNF) receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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decoy receptor 3

Target id: 2322

Nomenclature: decoy receptor 3

Systematic Nomenclature: TNFRSF6B

Family: Tumour necrosis factor (TNF) receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     decoy receptor 3 has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 300 20q13.33 TNFRSF6B TNF receptor superfamily member 6b
Previous and Unofficial Names
DCR3 | decoy receptor for Fas ligand | tumor necrosis factor receptor superfamily, member 6b, decoy | tumor necrosis factor receptor superfamily member 6b
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas


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1. Yang CR, Hsieh SL, Ho FM, Lin WW. (2005) Decoy receptor 3 increases monocyte adhesion to endothelial cells via NF-kappa B-dependent up-regulation of intercellular adhesion molecule-1, VCAM-1, and IL-8 expression. J. Immunol., 174 (3): 1647-56. [PMID:15661928]

2. Yang CR, Hsieh SL, Teng CM, Ho FM, Su WL, Lin WW. (2004) Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action. Cancer Res., 64 (3): 1122-9. [PMID:14871847]

How to cite this page

Tumour necrosis factor (TNF) receptor family: decoy receptor 3. Last modified on 25/04/2017. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY,