Interleukin-6 receptor, β subunit | IL-6 receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Interleukin-6 receptor, β subunit

Target id: 2317

Nomenclature: Interleukin-6 receptor, β subunit

Abbreviated Name: IL6ST

Systematic Nomenclature: interleukin 6 signal transducer

Family: IL-6 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     Interleukin-6 receptor, β subunit has curated data in GtoImmuPdb

Quaternary Structure: Complexes
Interleukin-6 receptor
Interleukin-11 receptor
Ciliary neutrophic factor receptor
Leukemia inhibitory factor receptor
Oncostatin-M receptor
Interleukin-27 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 918 5q11.2 IL6ST interleukin 6 signal transducer
Mouse 1 917 13 63.73 cM Il6st interleukin 6 signal transducer
Rat 1 918 2q14-q16 Il6st interleukin 6 signal transducer
Previous and Unofficial Names
CD130 | gp130 | interleukin-6 receptor subunit beta | membrane glycoprotein 130 | oncostatin-M receptor subunit alpha | interleukin 6 signal transducer (gp130, oncostatin M receptor)
Database Links
CATH/Gene3D
Ensembl Gene
Human Protein Atlas
OMIM
UniProtKB
Wikipedia
Selected 3D Structures
Image of receptor 3D structure from RCSB PDB
Description:  Cytokine-binding region of gp130
PDB Id:  1BQU
Resolution:  2.0Å
Species:  Human
References:  1

References

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1. Bravo J, Staunton D, Heath JK, Jones EY. (1998) Crystal structure of a cytokine-binding region of gp130. EMBO J., 17 (6): 1665-74. [PMID:9501088]

How to cite this page

IL-6 receptor family: Interleukin-6 receptor, β subunit. Last modified on 08/12/2017. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2317.