Thymic stromal lymphopoietin receptor | IL-2 receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Thymic stromal lymphopoietin receptor

Target id: 2305

Nomenclature: Thymic stromal lymphopoietin receptor

Family: IL-2 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     Thymic stromal lymphopoietin receptor has curated data in GtoImmuPdb

Quaternary Structure: Subunits
Interleukin-7 receptor subunit α (Ligand-binding subunit)
Cytokine receptor-like factor 2 (Other subunit)

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Agonists
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Affinity Units Reference
thymic stromal lymphopoietin {Sp: Human} Hs Agonist - -

References

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1. Cook EB, Stahl JL, Schwantes EA, Fox KE, Mathur SK. (2012) IL-3 and TNF╬▒ increase Thymic Stromal Lymphopoietin Receptor (TSLPR) expression on eosinophils and enhance TSLP-stimulated degranulation. Clin Mol Allergy, 10 (1): 8. [PMID:22838633]

2. Han NR, Oh HA, Nam SY, Moon PD, Kim DW, Kim HM, Jeong HJ. (2014) TSLP induces mast cell development and aggravates allergic reactions through the activation of MDM2 and STAT6. J. Invest. Dermatol., 134 (10): 2521-30. [PMID:24751726]

3. Migalovich-Sheikhet H, Friedman S, Mankuta D, Levi-Schaffer F. (2012) Novel identified receptors on mast cells. Front Immunol, 3: 238. [PMID:22876248]

4. Wong CK, Hu S, Cheung PF, Lam CW. (2010) Thymic stromal lymphopoietin induces chemotactic and prosurvival effects in eosinophils: implications in allergic inflammation. Am. J. Respir. Cell Mol. Biol., 43 (3): 305-15. [PMID:19843704]

How to cite this page

IL-2 receptor family: Thymic stromal lymphopoietin receptor. Last modified on 10/04/2017. Accessed on 16/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=2305.