lymphotoxin β receptor | Tumour necrosis factor (TNF) receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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lymphotoxin β receptor

Target id: 1872

Nomenclature: lymphotoxin β receptor

Systematic Nomenclature: TNFRSF3

Family: Tumour necrosis factor (TNF) receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     lymphotoxin β receptor has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 435 12p13 LTBR lymphotoxin beta receptor
Mouse 1 415 Ltbr lymphotoxin B receptor
Rat - - Ltbr lymphotoxin beta receptor
Previous and Unofficial Names
CD18 | LTbetaR | LT-beta receptor | LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | TNFCR | TNFR2-RP | TNF receptor-related protein | TNFR III
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Gene
OMIM
UniProtKB
Wikipedia
Adaptor proteins (Human)
TRAF3, TRAF4, TRAF5
Other Binding Ligands
Key to terms and symbols Click column headers to sort
Ligand Sp. Action Affinity Units Reference
LIGHT {Sp: Human} Hs - - -
lymphotoxin β2α1 heterotrimer {Sp: Human} N/A - - -

References

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1. Bienkowska J, Allaire N, Thai A, Goyal J, Plavina T, Nirula A, Weaver M, Newman C, Petri M, Beckman E et al.. (2014) Lymphotoxin-LIGHT pathway regulates the interferon signature in rheumatoid arthritis. PLoS ONE, 9 (11): e112545. [PMID:25405351]

2. Chang YH, Hsieh SL, Chen MC, Lin WW. (2002) Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation. Exp. Cell Res., 278 (2): 166-74. [PMID:12169272]

Contributors

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How to cite this page

David MacEwan.
Tumour necrosis factor (TNF) receptor family: lymphotoxin β receptor. Last modified on 26/03/2018. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY, http://guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1872.