NLRP10 | NOD-like receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Target id: 1777

Nomenclature: NLRP10

Family: NOD-like receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     NLRP10 has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 655 11p15.4 NLRP10 NLR family pyrin domain containing 10
Mouse - 673 7 57.21 cM Nlrp10 NLR family, pyrin domain containing 10
Rat - - 1q33 Nlrp10 NLR family, pyrin domain containing 10
Previous and Unofficial Names
NALP10 | NOD8 | PAN5 | Pynod | NACHT, leucine rich repeat and PYD containing 10 | NLR family, pyrin domain containing 10 | CLR11.1 | NLR family
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas
Physiological Functions Comments
Involved in antigen-presenting cell migration, T-Cell priming and NOD1 signalling enhancement.


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1. Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T. (2010) Anti-inflammatory activity of PYNOD and its mechanism in humans and mice. J. Immunol., 184 (10): 5874-84. [PMID:20393137]


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How to cite this page

Clare Bryant, Tom Monie.
NOD-like receptor family: NLRP10. Last modified on 22/03/2017. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY,