Interleukin-1 receptor-like 2 | Immunoglobulin-like family of IL-1 receptors | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Interleukin-1 receptor-like 2

Target id: 1736

Nomenclature: Interleukin-1 receptor-like 2

Family: Immunoglobulin-like family of IL-1 receptors

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     Interleukin-1 receptor-like 2 has curated data in GtoImmuPdb

Quaternary Structure: Complexes
Interleukin-36 receptor
Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 575 2q12.1 IL1RL2 interleukin 1 receptor like 2
Mouse 1 574 Il1rl2 interleukin 1 receptor-like 2
Rat 1 561 Il1rl2 interleukin 1 receptor-like 2
Previous and Unofficial Names
IL1RRP2 | interleukin-1 receptor-related protein 2
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas

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Antibody Sp. Action Affinity Units Reference
MAB92 Hs Antagonist 10.6 pKd 1
pKd 10.6 (Kd 2.4x10-11 M) [1]


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1. Ganesan R, Raymond EL, Mennerich D, Woska Jr JR, Caviness G, Grimaldi C, Ahlberg J, Perez R, Roberts S, Yang D et al.. (2017) Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies. MAbs, 9 (7): 1143-1154. [PMID:28726542]

How to cite this page

Immunoglobulin-like family of IL-1 receptors: Interleukin-1 receptor-like 2. Last modified on 08/08/2018. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY,