Interleukin-22 receptor α2 | IL-10 receptor family | IUPHAR Guide to IMMUNOPHARMACOLOGY

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Interleukin-22 receptor α2

Target id: 1732

Nomenclature: Interleukin-22 receptor α2

Family: IL-10 receptor family

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

   GtoImmuPdb view: ON :     Interleukin-22 receptor α2 has curated data in GtoImmuPdb

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 263 06q23.3 IL22RA2 interleukin 22 receptor subunit alpha 2
Mouse - 230 Il22ra2 interleukin 22 receptor, alpha 2
Rat - 229 Il22ra2 interleukin 22 receptor subunit alpha 2
Previous and Unofficial Names
CRF2-S1 | cytokine receptor family II soluble 1 | IL-22 receptor subunit alpha-2 | interleukin-22-binding protein | IL-22BP | interleukin 22 receptor, alpha 2 | interleukin 22 receptor
Database Links
Ensembl Gene
Entrez Gene
Human Protein Atlas


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1. de Moura PR, Watanabe L, Bleicher L, Colau D, Dumoutier L, Lemaire MM, Renauld JC, Polikarpov I. (2009) Crystal structure of a soluble decoy receptor IL-22BP bound to interleukin-22. FEBS Lett., 583 (7): 1072-7. [PMID:19285080]

2. Felix J, Savvides SN. (2017) Mechanisms of immunomodulation by mammalian and viral decoy receptors: insights from structures. Nat. Rev. Immunol., 17 (2): 112-129. [PMID:28028310]

How to cite this page

IL-10 receptor family: Interleukin-22 receptor α2. Last modified on 06/04/2017. Accessed on 18/01/2019. IUPHAR/BPS Guide to PHARMACOLOGY,